GenoLens — Genomic Variant Lookup

Highlight any gene, variant, disease, or trial on a webpage to see clinical annotations, cancer evidence, and recruiting trials.

GenoLens is a browser extension for clinical geneticists, genetic counselors, molecular pathologists, and bioinformatics researchers. Highlight a gene symbol, variant (rsID or HGVS), HPO term, or disease name on any webpage — or type it into the toolbar popup — and read multi-source genomic annotations in a compact tooltip, without leaving the page or switching tabs. Two ways to look up • Highlight any term on a page to open an in-place tooltip • Or click the toolbar icon and paste a term into the Look up box — handy for reports, PDFs, or anywhere a page selection is awkward What you can look up • Genes (BRCA1, TP53, CYP2D6) — approved nomenclature, diagnostic-panel confidence grades, gene–disease validity, protein function, and drug–gene interactions • Variants (rs121913527, or HGVS such as NM_004006.2:c.4375C>T) — clinical significance with review status, population allele frequencies, predicted molecular consequences, and linked literature • HPO terms (HP:0001639) — phenotype definitions and synonyms • Diseases (Hypertrophic cardiomyopathy) — associated genes with evidence scores and literature Follow related entities • Click any related gene, disease, or phenotype inside a result to look it up instantly — jump from a gene to its diseases, a disease to its genes, and back Cancer & oncology • A dedicated Cancer tab (shown when relevant) with somatic clinical evidence, driver-gene roles, mutation-hotspot context, and a protein-structure preview • AI Cancer Report: a concise, source-grounded summary for variants with oncology evidence Clinical trials • Actively recruiting trials for the gene or condition you're viewing, with phase and country filters and an optional sort-by-nearest • Framed as gene/condition-level exploration — not variant-level eligibility matching Pro — Trial Watch List • Subscribe a gene or disease to your watch list and get one weekly email when new recruiting trials appear • Manage watches and email preferences at genolens.app/dashboard/trials • One-click, no-login unsubscribe in every email Free vs Pro • All lookups, the Cancer tab, and live trial search are free — no account required • Pro adds the Trial Watch List with weekly new-trial alerts Data & citations GenoLens summarizes publicly available annotations from established genomic resources such as ClinVar, gnomAD, and ClinicalTrials.gov. The full list of data sources and their citations is published at genolens.app. Privacy • We do not read your browsing history or monitor page content • We process only the text you explicitly highlight or type into the popup • For Research Use Only — do not enter patient-identifiable data Permissions • "Read and change all your data on all websites" — required only to detect your text selection and draw the tooltip on the current page. The extension activates when you highlight text; it does not scan or transmit page content.