GenoLens — Genomic Variant Lookup

Highlight any gene, variant, or disease on a webpage to instantly see clinical annotations from 15 genomic databases.

GenoLens is a browser extension for clinical geneticists, genetic counselors, and bioinformatics researchers. Highlight any gene symbol, variant ID (rsID), HPO term, or disease name on any webpage to instantly view multi-source genomic annotations in a compact tooltip — no tab-switching required. **What you can look up:** • Gene symbols (BRCA1, TP53, CYP2D6) → HGNC nomenclature, PanelApp diagnostic grades, UniProt protein function, PharmGKB drug interactions, Open Targets disease associations • Variant IDs (rs121913527) → ClinVar pathogenicity with review stars, gnomAD population frequencies, Ensembl VEP functional predictions, AlphaMissense AI scores, LitVar2 publications • HPO terms (HP:0001639) → Phenotype definitions and synonyms • Disease names (Hypertrophic cardiomyopathy) → Associated genes with scores, relevant literature **Key features:** • Instant tooltip appears beside your text selection • 15 trusted data sources queried in parallel • Local caching for instant repeat lookups • Colorblind-accessible confidence indicators • Works on any webpage (PubMed, ClinVar, journals, EMRs) • No account required — all core features are free **Data sources:** HGNC, PanelApp, ClinVar, gnomAD, Ensembl VEP, LitVar2, Open Targets, HPO, Europe PMC, UniProt, PharmGKB, ClinGen, DDG2P, Orphanet, AlphaMissense **Privacy:** • We do NOT read your browsing history • We do NOT monitor page content • We ONLY process the text you explicitly highlight • No patient data should be entered — For Research Use Only **Permissions explained:** • "Read and change all your data on all websites" — Required to detect text selections and display the tooltip overlay on any webpage. We only activate when you highlight text.